Nodular colonic lesion in a nephrectomized patient.

A 54 years old man casually diagnosed with right renal hypernephroma underwent a radical right nephrectomy seven years ago. The pathologic exam confirmed a clear cell carcinoma. In the follow up study, an abdominal CT demonstrated metastasis shaped lesions in liver and left kidney and a hypervascular colonic nodular lesion (Fig. 1). A colonoscopy was performed. The pathologic study of the colonic biopsies confirmed the presence of a clear cell carcinoma metastasis (immunohistochemistry was positive for cytokeratin AE1, AE3, vimentin, and focally CD10). Extension study was completed. Surgical treatment was not indicated and for an indefinite period of time sunitinib treatment was initiated.